Recombinant human ADBR2-Gia3 protein (ab90373)

製品の概要

  • 製品名Recombinant human ADBR2-Gia3 protein
  • タンパク質長Full length protein

法規制情報

製品の詳細

  • 由来Recombinant
  • 由来Baculovirus infected Sf9 cells
  • アミノ酸配列
    • アクセッション番号P07550
    • 生物種Human
    • 配列の追加情報Tagged at the N terminus of the ADBR2 with a DDDDK tag. The C terminus of the ADBR2 is linked to the N terminus of the Gia3 with a His tag. 90kDa + 36kDa.

特性

Our Abpromise guarantee covers the use of ab90373 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性

    Receptor expression level: 5.4 pmol/mg

  • アプリケーション

    Functional Studies

  • 製品の状態Liquid
  • 備考Receptor expression level: 5.4 pmol/mg.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 75mM Tris HCl, 12.5mM Magnesium chloride, 1mM EDTA, pH 7.4

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

関連情報

  • 関連性ADBR2 + Gia3 is a fusion protein in which the Gia3 N-terminus is linked to the ADBR2 C-terminus via a His-tag. The ADBR2 is activated by the catecholaine epinephrine and couples to the G-protein G s to mediate adenylate cyclase activation. ADBR2 is found in numerous tissues and cell types including vascular and bronchial smooth muscle cells, leukocytes and liver. ADBR2 mediates smooth muscle relaxation, inhibition of leukocyte function and activation or glycogenolysis. In addition to Gs-proteins, ADBR2 can also couple to Gi-proteins. The ADBR2-Gia3 fusion protein ensures a defined 1:1 stoichiometry of the receptor and the Gia3 subunit.

Recombinant human ADBR2-Gia3 protein (ab90373) 使用論文

ab90373 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"