Recombinant Human Activin A Receptor Type IC protein (ab125628)

製品の概要

法規制情報

製品の詳細

  • 由来
    Recombinant
  • 由来
    Baculovirus infected Sf9 cells
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 分子量
      68 kDa including tags
    • 領域
      135 to 493

特性

Our Abpromise guarantee covers the use of ab125628 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Western blot

    SDS-PAGE

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.31% Glutathione, 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 0.003% EDTA, 25% Glycerol, 0.88% Sodium chloride

関連情報

  • 別名
    • Activin A receptor, type IC
    • Activin receptor like kinase 7
    • Activin receptor type 1C precursor
    • Activin receptor type IC
    • Activin receptor type-1C
    • Activin receptor-like kinase 7
    • ACTR IC
    • ACTR-IC
    • ACTRIC
    • ACV1C_HUMAN
    • Acvr1c
    • ACVRLK7
    • ALK 7
    • ALK-7
    • ALK7
    see all
  • 機能
    Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
  • 組織特異性
    Present in pancreas, heart, colon, small intestine, ovary and the hippocampus, medulla oblongata and putamen of the brain. Isoform 1, isoform 2, isoform 3 and isoform 4 are all expressed in the placenta throughout pregnancy.
  • 配列類似性
    Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
    Contains 1 GS domain.
    Contains 1 protein kinase domain.
  • 細胞内局在
    Membrane.
  • Information by UniProt

Recombinant Human Activin A Receptor Type IC protein 画像

  • SDS-PAGE of Human Activin A Receptor Type IC.

Recombinant Human Activin A Receptor Type IC protein (ab125628) 使用論文

ab125628 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab125628.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録