Recombinant human active Caspase 2 protein (ab52098)

製品の概要

  • 製品名Recombinant human active Caspase 2 protein
  • タンパク質長Full length protein

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 生物種Human

特性

Our Abpromise guarantee covers the use of ab52098 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性SPECIFIC ACTIVITY: 10,000 – 13,000 units/mg UNIT DEFINATION: One unit of the recombinant caspase-2 is the enzyme activity that cleaves 1 nmol of the caspase substrate VDVAD-pNA (pNA: pnitroanaline) per hour at 37oC in a reaction solution containing 50 mM Hepes, pH 7.2, 50 mM NaCl, 0.1% Chaps, 10 mM EDTA, 5% Glycerol, and 10 mM DTT
  • アプリケーション

    Western blot

    SDS-PAGE

    Functional Studies

  • 精製度> 95 % SDS-PAGE.

  • 製品の状態Lyophilised
  • 備考The lyophilized caspase-2 is stable for 1 year at –70oC.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 15% Glycerol, PBS

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 再構成Reconstitute to 1 unit per µl in PBS containing 15% glycerol.

関連情報

  • 別名
    • CASP2
    • Caspase 2
    • ICH 1L
    • ICH1
    • ICH1 protease
    • ICH1L
    • NEDD 2 apoptosis regulatory gene
    • NEDD2
    see all
  • 関連性Caspase 2 is involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. During apoptosis, procaspase-2 is processed at aspartate residues. The processed form of caspase-2 consists of large (19 kDa) and small (12 kDa) subunits which associate to form the active enzyme.
  • 細胞内局在Cytosol, membrane

Recombinant human active Caspase 2 protein (ab52098) 使用論文

ab52098 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"