製品の概要
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製品名Recombinant Human ABCB5 protein
ABCB5 タンパク質・ペプチド 製品一覧 -
タンパク質長Protein fragment
製品の詳細
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由来Recombinant
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由来Escherichia coli
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アミノ酸配列
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アクセッション番号
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生物種Human
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配列ILRGLSLSIERGKTVAFVGSSGCGKSTSVQLLQRLYDPVQGQVLFDGVDA KELNVQWLRSQIAIVPQEPVLFNCSIAENIAYGDNSRVVPLDEIKEAANA ANIHSFIEGLPEKYNTQVGLKGAQLSGGQKQRLAIARALLQKPKILLLDE ATSALDNDSEKVVQHALDKARTGRTCLVVTHRLSAIQNADLIVVLHNGKI KEQG
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領域587 to 790
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特性
Our Abpromise guarantee covers the use of ab125989 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
SDS-PAGE
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製品の状態Lyophilised
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Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Store at -20°C.
Constituents: 0.32% Tris HCl, 0.58% Sodium chloride, 28.8% Guanidine HCl
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再構成Reconstitute with water to desired concentration.
関連情報
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別名
- ABCB 5
- ABCB5
- ABCB5 P-gp
see all -
機能Plasma membrane transporter able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Responsible for the resistance to doxorubicin of a subset of malignant melanomas.
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組織特異性Expressed by CD133-expressing progenitor cells among epidermal melanocytes (at protein level). Widely expressed with specific expression in pigment cells. Also expressed in several malignant tissues.
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配列類似性Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
Contains 1 ABC transmembrane type-1 domain.
Contains 2 ABC transporter domains. -
細胞内局在Cell membrane.
- Information by UniProt
Recombinant Human ABCB5 protein (ab125989) 使用論文
ab125989 has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"