Recombinant Human 5 Lipoxygenase protein (ab114310)

製品の概要

  • 製品名Recombinant Human 5 Lipoxygenase protein
  • タンパク質長Full length protein

製品の詳細

  • 由来Recombinant
  • 由来Wheat germ
  • アミノ酸配列
    • アクセッション番号P09917
    • 生物種Human
    • 配列MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGA VDSYDVTVDEELGEIQLVRIEKRKYWLNDDWYLKYITLKTPHGDYIEFPC YRWITGDVEVVLRDGRAKLARDDQIHILKQHRRKELETRQKQYRWMEWNP GFPLSIDAKCHKDLPRDIQFDSEKGVDFVLNYSKAMENLFINRFMHMFQS SWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNGCNPVLIRRCT ELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDP CTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLPSDAKYDWLL AKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAH VRFTIAINTKAREQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLC FPEAIKARGMESKEDIPYYFYRDDGLLVWEAIRTFTAEVVDIYYEGDQVV EEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQ HAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCW HLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIA ERNKKKQLPYYYLSPDRIPNSVAI
    • 分子量100 kDa including tags
    • 領域1 to 674

特性

Our Abpromise guarantee covers the use of ab114310 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Western blot

    ELISA

  • 製品の状態Liquid
  • 備考Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.3% Glutathione

関連情報

  • 別名
    • 5 LO
    • 5 LOX
    • 5-lipoxygenase
    • 5-LO
    • 5-LOX
    • 5LOX
    • 5LPG
    • ALOX 5
    • Alox5
    • Arachidonate 5 lipoxygenase
    • Arachidonate 5-lipoxygenase
    • arachidonic 5-lipoxygenase alpha-10 isoform
    • arachidonic 5-lipoxygenase delta-10-13 isoform
    • arachidonic 5-lipoxygenase delta-13 isoform
    • arachidonic 5-lipoxygenase delta-p10 isoform
    • Arachidonic acid 5 lipoxygenase
    • Leukotriene A4 synthase
    • LOG 5
    • LOG5
    • LOX5_HUMAN
    • MGC163204
    see all
  • 機能Catalyzes the first step in leukotriene biosynthesis, and thereby plays a role in inflammatory processes.
  • パスウェイLipid metabolism; leukotriene A4 biosynthesis.
  • 配列類似性Belongs to the lipoxygenase family.
    Contains 1 lipoxygenase domain.
    Contains 1 PLAT domain.
  • 翻訳後修飾Serine phosphorylation by MAPKAPK2 is stimulated by arachidonic acid. Phosphorylation on Ser-523 by PKA has an inhibitory effect. Phosphorylation on Ser-272 prevents export from the nucleus.
  • 細胞内局在Cytoplasm. Nucleus matrix. Nucleus membrane. Shuttles between cytoplasm and nucleus. Found exclusively in the nucleus, when phosphorylated on Ser-272. Calcium binding promotes translocation from the cytosol and the nuclear matrix to the nuclear envelope and membrane association.
  • Information by UniProt

Recombinant Human 5 Lipoxygenase protein 画像

  • SDS-PAGE analysis of ab114310 on a 12.5% gel stained with Coomassie Blue.

Recombinant Human 5 Lipoxygenase protein (ab114310) 使用論文

ab114310 has not yet been referenced specifically in any publications.

Product Wall

Te pido disculpas por la espera.

He confirmado con mis compañeros del laboratorio que la proteína ab114310 puede también utilizarse como control positivo para el anticuerpo ab59341.

Si tuvieras cualquier otra co...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"