Recombinant Human 14-3-3 Tau protein (ab85978)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号P27348
    • 生物種Human
    • 配列MEKTELIQKA KLAEQAERYD DMATCMKAVT EQGAELSNEE RNLLSVAYKN VVGGRRSAWR VISSIEQKTD TSDKKLQLIK DYREKVESEL RSICTTVLEL LDKYLIANAT NPESKVFYLK MKGDYFRYLA EVACGDDRKQ TIDNSQGAYQ EAFDISKKEM QPTHPIRLGL ALNFSVFYYE ILNNPELACT LAKTAFDEAI AELDTLNEDS YKDSTLIMQL LRDNLTLWTS DSAGEECDAA EGAEN
    • 分子量27 kDa
    • 領域1 to 245

特性

Our Abpromise guarantee covers the use of ab85978 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度> 95 % SDS-PAGE.
    ab85978 was purified using conventional chromatography techniques.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Avoid freeze / thaw cycle.

    pH: 7.4
    Constituents: Phosphate Buffer, 10% Glycerol

関連情報

  • 別名
    • 14 3 3 protein T cell
    • 14 3 3 protein tau
    • 14 3 3 protein theta
    • 14 3 3 tau
    • 14 3 3 theta
    • 14-3-3 protein T-cell
    • 14-3-3 protein tau
    • 14-3-3 protein theta
    • 1433T_HUMAN
    • 1C5
    • HS1
    • KCIP1
    • Protein HS1
    • Protein kinase C inhibitor protein 1
    • Protein tau
    • tyr3/trp5 monooxygenase activation protein, theta
    • Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, theta polypeptide
    • Ywhaq
    see all
  • 機能Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
  • 組織特異性Abundantly expressed in brain, heart and pancreas, and at lower levels in kidney and placenta. Up-regulated in the lumbar spinal cord from patients with sporadic amyotrophic lateral sclerosis (ALS) compared with controls, with highest levels of expression in individuals with predominant lower motor neuron involvement.
  • 配列類似性Belongs to the 14-3-3 family.
  • 翻訳後修飾Ser-232 is probably phosphorylated by CK1.
  • 細胞内局在Cytoplasm. In neurons, axonally transported to the nerve terminals.
  • Information by UniProt

Recombinant Human 14-3-3 Tau protein 画像

  • 15% SDS-PAGE showing ab85978 at approximately 27kDa (3µg).

Recombinant Human 14-3-3 Tau protein (ab85978) 使用論文

ab85978 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab85978.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"