Recombinant Human 14-3-3 sigma protein (ab40599)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Escherichia coli
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Human
    • 配列
      MERASLIQKA KLAEQAERYE DMAAFMKGAV EKGEELSCEE RNLLSVAYKN VVGGQRAAWR VLSSIEQKSN EEGSEEKGPE VREYREKVET ELQGVCDTVL GLLDSHLIKE AGDAESRVFY LKMKGDYYRY LAEVATGDDK KRIIDSARSA YQEAMDISKK EMPPTNPIRL GLALNFSVFH YEIANSPEEA ISLAKTTFDE AMADLHTLSE DSYKDSTLIM QLLRDNLTLW TADNAGEEGG EAPQEPQS
    • 分子量
      28 kDa
    • タグ
      His tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab40599 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度
    > 95 % SDS-PAGE.

  • 製品の状態
    Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: 0.002% Sodium Azide
    Constituents: 3mM Sodium chloride, 10mM Tris, 2.5mM Imidazole, pH 8

関連情報

  • 別名
    • 14 3 3 protein sigma
    • 14-3-3 protein sigma
    • 1433S_HUMAN
    • Epithelial cell marker protein 1
    • Er
    • HME 1
    • HME1
    • MGC143283
    • Mkrn3
    • Mme1
    • OTTHUMP00000004242
    • RP23 137L22.11
    • SFN
    • SFN protein
    • Stratifin
    • YWHAS
    see all
  • 機能
    Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.
    p53-regulated inhibitor of G2/M progression.
  • 組織特異性
    Present mainly in tissues enriched in stratified squamous keratinizing epithelium.
  • 配列類似性
    Belongs to the 14-3-3 family.
  • 翻訳後修飾
    Ubiquitinated. Ubiquitination by RFFL induces proteasomal degradation and indirectly regulates p53/TP53 activation.
  • 細胞内局在
    Cytoplasm. Nucleus. Secreted. May be secreted by a non-classical secretory pathway.
  • Information by UniProt

Recombinant Human 14-3-3 sigma protein 画像

  • Analysis of 14-3-3 sigma Recombinant protein. 4-20% SDS gradient gel. Coomassie blue staining. Band size approximately 28 kDa.

Recombinant Human 14-3-3 sigma protein (ab40599) 使用論文

ab40599 has not yet been referenced specifically in any publications.

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