Recombinant HIV2 gp36 protein (Beta-Galactosidase) (ab49057)

製品の概要

法規制情報

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • 配列の追加情報Fused with β-galactosidase at the N-terminus.

特性

Our Abpromise guarantee covers the use of ab49057 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性Reacts strongly with human HIV positive sera.
  • アプリケーション

    ELISA

    Western blot

  • 精製度> 95 % SDS-PAGE.

  • 製品の状態Liquid
  • 備考Reacts strongly with human HIV positive sera.
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 0.05% Tween 20, 0.014M Beta mercaptoethanol, 0.01M Sodium carbonate, 0.01M EDTA

関連情報

  • 別名
    • Gp36
    • HIV 2
    • Human immunodeficiency virus 2
  • 関連性HIV2 infections at present, are predominantly found in west Africa where it is the dominant form of HIV. Both HIV1 and HIV2 have the same modes of transmission and are associated with similar opportunistic infections and AIDS. In persons infected with HIV2, immunodeficiency seems to develop more slowly and to be milder, but as the disease advances, HIV2 infectiousness seems to increase. Little is known about the best approach to the clinical treatment and care of patients infected with HIV2. Some drugs used to treat HIV1 are ineffective. HIV1 and HIV2 have similar gag (viral core) and pol (polymerase) regions, they have relatively dissimilar env (envelope) regions. Owing to this lack of homology in the envelope region, there is little serologic cross-reactivity of the antibodies directed against the envelope antigens of both HIV1 and HIV2. The env gp36 ectodomain is highly conserved and elicits a type-specific antibody response. Hence, most licensed diagnostic assays incorporate gp36-derived antigens to detect HIV2 specific antibodies. It is becoming important to differentiate between single infection with either HIV1 or HIV2 and dual infection.

Recombinant HIV2 gp36 protein (Beta-Galactosidase) (ab49057) 使用論文

ab49057 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"