Recombinant HA1 (H9N2) protein (ab67740)

製品の概要

  • 製品名Recombinant HA1 (H9N2) protein
  • タンパク質長Full length protein

法規制情報

製品の詳細

  • 由来Recombinant
  • 由来Baculovirus infected insect cells

特性

Our Abpromise guarantee covers the use of ab67740 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Western blot

    ELISA

  • 精製度> 90 % SDS-PAGE.
    sterile filtered.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 0.01% Tween 20, 150mM Sodium chloride, 10mM Sodium phosphate, pH 7.0

関連情報

  • 別名
    • Hemagglutinin
  • 関連性Hemagglutinin (HA) is a class I viral fusion protein from the Influenza virus. It is a major glycoprotein, comprising over 80% of the envelope proteins present in the virus particle. HA binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell, and is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. The HA protein is a homotrimer of disulfide-linked HA1-HA2. It also plays a major role in the determination of host range restriction and virulence. Genetic variation of hemagglutinin and/or neuraminidase genes results in the emergence of new influenza strains. Influenza A subtypes are classified based on the combination of the virus coat glycoproteins, hemagglutinin (HA) and neuraminidase (NA). H9N2 influenza A viruses circulate worldwide. Since the mid-1990s, H9 viruses have become adapted to land-based birds and have crossed sporadically to pigs and humans, causing mild respiratory disease. Importantly, some of the currently circulating H9N2 viruses bind to sialic acid receptors linked to galactose in the {alpha}-2,6 conformation, which is the preferential binding pattern of human influenza viruses. Thus, these H9N2 viruses possess one of the key elements needed to establish stable lineages in humans.
  • 細胞内局在viral envelope; apical plasma membrane. Associated with glycosphingolipid- and cholesterol-enriched detergent-resistant lipid rafts (By similarity).

Recombinant HA1 (H9N2) protein (ab67740) 使用論文

ab67740 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your inquiry. The protein is made in SF+ cells - a proprietary cell line. Also, the cell media is serum free. I hope this information helps. Please contact us with any other questions.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"