Recombinant Guinea pig HRH1 protein (ab90420)

製品の概要

法規制情報

製品の詳細

  • 由来Recombinant
  • 由来Insect cells
  • アミノ酸配列
    • 生物種Guinea pig

特性

Our Abpromise guarantee covers the use of ab90420 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Functional Studies

  • 製品の状態Liquid
  • 備考


    Small HRH1 agonists exhibit similar effects at Human HRH1 and guinea pig HRH1, whereas bulkier 2-phenylhistamines and histaprodifens are up to ~10-fold more potent at guinea pig HRH1 than at Human HRH1. Several first-generation HRH1 antagonists are ~2-fold, and arpromidine-type HRH1 antagonists up to ~10-fold more potent at guinea pig HRH1 than at Human HRH1.

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前処理および保存

  • 保存方法および安定性

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 75mM Tris HCl, 12.5mM Magnesium chloride, 1mM EDTA, pH 7.4

関連情報

  • 別名
    • BPHS, mouse, homolog of
    • H1 R
    • H1R
    • HH1R
    • HisH1
    • Histamine H(1) receptor
    • Histamine H1 receptor
    • Histamine receptor H1
    • Histamine receptor subclass H1
    • Hrh1
    • HRH1_HUMAN
    see all
  • 機能In peripheral tissues, the H1 subclass of histamine receptors mediates the contraction of smooth muscles, increase in capillary permeability due to contraction of terminal venules, and catecholamine release from adrenal medulla, as well as mediating neurotransmission in the central nervous system.
  • 配列類似性Belongs to the G-protein coupled receptor 1 family.
  • 翻訳後修飾Potential sites of phosphorylation in the third cytoplasmic loop may play an important role in regulating signal transduction through the receptor molecule.
  • 細胞内局在Cell membrane.
  • Information by UniProt

Recombinant Guinea pig HRH1 protein (ab90420) 使用論文

ab90420 has not yet been referenced specifically in any publications.

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