Recombinant E. coli Nitroreductase protein (ab97948)

製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli
  • アミノ酸配列
    • アクセッション番号P38489
    • 生物種Escherichia coli
    • 配列MGSSHHHHHHSSGLVPRGSHMDIISVALKRHSTKAFDASKKLTPEQAEQI KTLLQYSPSSTNSQPWHFIVASTEEGKARVAKSAAGNYVFNERKMLDASH VVVFCAKTAMDDVWLKLVVDQEDADGRFATPEAKAANDKGRKFFADMHRK DLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAEFGLKE KGYTSLVVVPVGHHSVEDFNATLPKSRLPQNITLTEV
    • 分子量26 kDa including tags
    • 領域1 to 217
    • タグHis tag N-Terminus

特性

Our Abpromise guarantee covers the use of ab97948 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

    Mass Spectrometry

  • 精製度> 95 % SDS-PAGE.
    ab97948 is purified using conventional chromatography techniques.
  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 50mM Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0

関連情報

  • 別名
    • Dihydropteridine reductase
    • dprA
    • FMN dependent nitroreductase
    • nfnB
    • nfsI
    • ntr
    • Oxygen insensitive NAD(P)H nitroreductase
    see all
  • 関連性Nitroreductase shows the ability to reduce quinines. It is an enzyme for activating prodrugs in antibody directed enzyme prodrug therapy. It is also capable of reducing nitrofurazone, quinones and the anti-tumor agent CB1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide). The reduction of CB1954 results in the generation of cytotoxic species.

Recombinant E. coli Nitroreductase protein 画像

  • 15% SDS-PAGE showing ab97948 at approximately 26kDa (3µg).

Recombinant E. coli Nitroreductase protein (ab97948) 使用論文

ab97948 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"