製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Yeast
  • アミノ酸配列
    • アクセッション番号
    • 生物種
      Dog
    • 配列
      HKSSFQEQDL LLIRMRQLID IVDQLKNYVN DLDPESLPAP EDVKRHCERS AFSCFQKVQL KAANTGGNEQ IINVLTKQLK RKLPPTNAGR RQKHRPACPS CDSYEKAPPK EFLERLKSLI QKMIHQHLS
    • 分子量
      15 kDa
    • 領域
      18 to 146

特性

Our Abpromise guarantee covers the use of ab101290 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度
    > 95 % SDS-PAGE.
    ab101290 was purified by ion-exchange chromatography
  • 製品の状態
    Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Trehalose, 1X PBS

  • 再構成
    Reconstitute with sterile PBS containing at least 0.1% carrier protein (BSA)

関連情報

  • 別名
    • CVID11
    • IL 21
    • IL-21
    • Il21
    • IL21_HUMAN
    • Interleukin 21
    • Interleukin-21
    • interleukin-21 isoform
    • Interleukin21
    • OTTHUMP00000164088
    • Za11
    see all
  • 機能
    Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG(1) and IgG(3) in B-cells (By similarity). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.
  • 組織特異性
    Expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes.
  • 配列類似性
    Belongs to the IL-15/IL-21 family.
  • 細胞内局在
    Secreted.
  • Information by UniProt

参考文献

ab101290 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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