The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Immunohistochemistry (Frozen sections)
エンドトキシン・レベル< 0.100 Eu/µg
備考The biological activity of this product was determined by its ability to chemoattract total human neutrophils using a concentration range of 1.0-10.0 ng/ml
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Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
This product is an active protein and may elicit a biological response in vivo, handle with caution.
C-X-C motif chemokine 2
Chemokine (C X C motif) ligand 2
Chemokine, CXC motif, ligand 2
Cytokine-induced neutrophil chemoattractant 3
GRO protein, beta
Growth regulated protein beta
Growth-regulated protein beta
Hematopoietic synergistic factor
Macrophage inflammatory protein 2
Macrophage inflammatory protein 2 alpha
Macrophage inflammatory protein 2-alpha
Melanoma growth stimulatory activity beta
Small inducible cytokine subfamily B, member 2
機能Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.
配列類似性Belongs to the intercrine alpha (chemokine CxC) family.
翻訳後修飾The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells.
Xu J et al. Limited role for CXC chemokines in the pathogenesis of alpha-naphthylisothiocyanate-induced liver injury. Am J Physiol Gastrointest Liver Physiol287:G734-41 (2004).
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