Recombinant cow IL4 protein (ab87679)

製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Yeast
  • アミノ酸配列
    • 生物種
      Cow
    • 配列
      GHKCDITLAE IIKTLNILTT RKNSCMELPV ADVFAAPKNT TEKETFCRVG IELRRIYRSH TCLNKFLGGL DRNLNSLASK TCSVNEAKTS TSTLKDLLER LKTIMKEKYS KC

特性

Our Abpromise guarantee covers the use of ab87679 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性
    The biological activity of ab87679 was measured in a cell proliferation assay using the Human TF1 cell line. The ED50 for this effect is typically 1.5 - 2 ng/mL.
  • アプリケーション

    Functional Studies

    SDS-PAGE

  • 製品の状態
    Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Trehalose, 1X PBS

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 再構成
    Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.

関連情報

  • 別名
    • B cell growth factor 1
    • B cell IgG differentiation factor
    • B Cell Stimulatory Factor 1
    • B-cell stimulatory factor 1
    • BCGF 1
    • BCGF1
    • Binetrakin
    • BSF-1
    • BSF1
    • IGG1 induction factor
    • IL 4
    • IL-4
    • IL4
    • IL4_HUMAN
    • Il4e12
    • Interleukin 4
    • Interleukin 4 variant 2
    • Interleukin 4, isoform 1
    • Interleukin-4
    • Lymphocyte stimulatory factor 1
    • MGC79402
    • Pitrakinra
    see all
  • 機能
    Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.
  • 関連疾患
    Genetic variations in IL4 may be a cause of susceptibility to ischemic stroke (ISCHSTR) [MIM:601367]; also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors.
  • 配列類似性
    Belongs to the IL-4/IL-13 family.
  • 細胞内局在
    Secreted.
  • Information by UniProt

参考文献

ab87679 has not yet been referenced specifically in any publications.

レビューと Q&A

Thank you for contacting us. The ED50 is an expression of activity at 50% of its maximum response. Specific activity is just another way of conveying the activity of the protein. To calculate a specific activity, divide 1 x 106 by the ED50 in ng/ml...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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