製品の概要

製品の詳細

  • 由来Recombinant
  • 由来Yeast
  • アミノ酸配列
    • 生物種Cow
    • 配列RAVSEDSSPA WTRGQQLSQQ LCMLAWSAHL PMGHMDLPRE EGGDKTTDDV PRIQCEDGCD PQGLRDNSQS CLQRIHRGLV FYEKLLGSDI FTGEPSLLPN GPVDQLHASI LGLRELLQPK GHHWETEQTP SPIPSQPWQR LLLRLKILRS LQAFVAVAAR VFAHGAATLS P

特性

Our Abpromise guarantee covers the use of ab87524 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 精製度> 95 % SDS-PAGE.
    ab87524 is purified by Ion-exchange chromatography.
  • 製品の状態Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

    Preservative: None
    Constituents: 10% Trehalose, 1X PBS

  • 再構成Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein. Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.

関連情報

  • 別名
    • IL 23
    • IL 23 A
    • IL 23 subunit alpha
    • IL 23A
    • IL 23p19
    • IL-23 subunit alpha
    • IL-23-A
    • IL-23p19
    • IL12B
    • IL23
    • Il23a
    • IL23A_HUMAN
    • IL23P19
    • interleukin 12B
    • Interleukin 23 alpha subunit p19
    • Interleukin 23 p19 subunit
    • interleukin 23 subunit alpha
    • interleukin 23 subunit p19
    • interleukin six, G CSF related factor
    • Interleukin-23 subunit alpha
    • Interleukin-23 subunit p19
    • JKA3 induced upon T cell activation
    • MGC79388
    • P19
    • SGRF
    see all
  • 機能Associates with IL12B to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to an heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
  • 組織特異性Secreted by activated dendritic and phagocytic cells and keratinocytes. Also expressed by dermal Langerhans cells (at protein level).
  • 配列類似性Belongs to the IL-6 superfamily.
  • 発生段階Expressed by newborns dendritic cells.
  • 細胞内局在Secreted. Secreted upon association with IL12B.
  • Information by UniProt

Recombinant Cow IL23 protein (ab87524) 使用論文

ab87524 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab87524.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"