製品の概要

製品の詳細

  • 由来
    Recombinant
  • 由来
    Saccharomyces cerevisiae
  • アミノ酸配列
    • 生物種
      Cow
    • 配列
      FPMFKGGRCL CIGPGVKAVK VADIEKVSII YPTNNCDKTE VIITLKTHKG QRCLNPKAKQ AKAIIKKVQR KNSEKYKNI

特性

Our Abpromise guarantee covers the use of ab88003 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生理活性
    The biological activity of ab88003 was determined in a chemotaxis assay using a Boyden chamber with bovine PBMC following initial culture with IL2. Bioactivity is typically detected at 25 ng/mL.
  • アプリケーション

    Functional Studies

    SDS-PAGE

  • 精製度
    > 95 % SDS-PAGE.
    ab88003 was purified using Ion-exchange chromatography
  • 製品の状態
    Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Trehalose, 1X PBS

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 再構成
    Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.

関連情報

  • 別名
    • b R1
    • b-R1
    • Beta-R1
    • betaR1
    • C-X-C motif chemokine 11
    • Chemokine (C-X-C motif) ligand 11
    • Chemokine C-X-C motif ligand 11
    • CXC11
    • CXCL11
    • CXL11_HUMAN
    • H174
    • I TAC
    • I-TAC
    • Interferon gamma inducible protein 9
    • Interferon gamma-inducible protein 9
    • Interferon inducible T cell alpha chemoattractant
    • Interferon-inducible T-cell a chemoattractant I-TAC
    • Interferon-inducible T-cell alpha chemoattractant
    • IP 9
    • IP-9
    • IP9
    • ITAC
    • MGC102770
    • SCYB11
    • SCYB9B
    • Small inducible cytokine B11
    • Small inducible cytokine subfamily B (Cys-X-Cys) member 11
    • Small inducible cytokine subfamily B (Cys-X-Cys) member 9B
    • Small inducible cytokine subfamily B, member 11
    • Small inducible cytokine subfamily B, member 9B
    • Small-inducible cytokine B11
    see all
  • 機能
    Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.
  • 組織特異性
    High levels in peripheral blood leukocytes, pancreas and liver astrocytes. Moderate levels in thymus, spleen and lung. Low levels in placenta, prostate and small intestine. Also found in epidermal basal layer keratinocytes in skin disorders.
  • 配列類似性
    Belongs to the intercrine alpha (chemokine CxC) family.
  • 細胞内局在
    Secreted.
  • Information by UniProt

参考文献

ab88003 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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