製品の概要

  • 製品名Recombinant Agitoxin2 protein
  • タンパク質長Full length protein

製品の詳細

  • 由来Recombinant
  • 由来Escherichia coli

特性

Our Abpromise guarantee covers the use of ab57372 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    SDS-PAGE

  • 製品の状態Lyophilised
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

    Preservative: None
    Constituents: 0.1% BSA, 100mM Sodium chloride, 10mM Tris, 1mM EDTA, pH 7.5

  • 再構成Reconstitute with 10 mM Tris, pH 7.5, containing 100 mM sodium chloride, 0.1% bovine serum albumin and 1 mM EDTA.

関連情報

  • 別名
    • Agitoxin 2
    • AgTx 2
    • AgTx2
    • Potassium channel toxin alpha KTx 3.2
  • 関連性Agitoxin is a toxin found in the venom of the scorpion Leiurus quinquestriatus herbraeus (yellow scorpion). Agitoxin binds to the Shaker K+ channel in Drosophila as well as to its mammalian homologue. It blocks this channel by binding with high affinity (Kd < 1 nM) to its external vestibule. Its structure consists of a triple-stranded antiparallel beta-sheet and a single helix covering one face of the beta-sheet. The cysteine side chains connect the beta-sheet and the helix form to the core of the molecule. The fold of agitoxin is homologous to the previously determined folds of scorpion venom toxins. Three types of agitoxin can be distinguished; all 3 agitoxins have been identified as 38 amino acid toxins (cystine bonds not shown): Agitoxin-2 Gly-Val-Pro-Ile-Asn-Val-Ser-Cys-Thr-Gly-Ser-Pro-Gln-Cys-Ile-Lys-Pro-Cys-Lys-Asp-Ala-Gly-Met-Arg-Phe-Gly-Lys-Cys-Met-Asn-Arg-Lys-Cys-His-Cys-Thr-Pro-Lys Molecular Formula = 169H278N54O48S8
  • 細胞内局在Secreted

Recombinant Agitoxin2 protein (ab57372) 使用論文

ab57372 has not yet been referenced specifically in any publications.

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