製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to REA
  • アプリケーション
    適用あり: WB, ICC/IFmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Rat, Cow
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 45-298 of Human REA (NP_009204)

  • ポジティブ・コントロール
    • H1299 and HeLa whole cell lysates; A431 cells; 293T, HepG2, Molt-4 and Raji cell lines

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab97538 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 33 kDa.
ICC/IF 1/100 - 1/200.

ターゲット情報

  • 機能
    Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
  • 配列類似性
    Belongs to the prohibitin family.
  • 発生段階
    Levels of expression in fibroblasts decrease heterogeneously during cellular aging.
  • 細胞内局在
    Mitochondrion inner membrane. Cytoplasm. Nucleus. Also cytoplasmic and nuclear.
  • Information by UniProt
  • 参照データベース
  • 別名
    • B cell receptor associated protein BAP37 antibody
    • B-cell receptor-associated protein BAP37 antibody
    • BAP antibody
    • Bap37 antibody
    • BCAP 37 antibody
    • D prohibitin antibody
    • D-prohibitin antibody
    • p22 antibody
    • Phb2 antibody
    • PHB2_HUMAN antibody
    • PNAS 141 antibody
    • Prohibitin 2 antibody
    • Prohibitin-2 antibody
    • Repressor of estrogen receptor activity antibody
    see all

画像

  • All lanes : Anti-REA antibody (ab97538) at 1/1000 dilution

    Lane 1 : H1299 whole cell lysate
    Lane 2 : HeLa whole cell lysate

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 33 kDa
  • Immunofluorescence analysis of paraformaldehyde-fixed A431, using ab97538 at 1/200 dilution (1) and merged with DNA probe (2).

参考文献

ab97538 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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