製品の概要

  • 製品名Anti-RBM5 antibody
    RBM5 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to RBM5
  • アプリケーション適用あり: IHC-P, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 75-184 of Human RBM5

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab56598 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Component of the spliceosome A complex. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.
    • 組織特異性Isoform 5 is widely expressed in normal tissues and is expressed at increased levels in T-leukemic cell lines.
    • 配列類似性Belongs to the RBM5/RBM10 family.
      Contains 1 C2H2-type zinc finger.
      Contains 1 G-patch domain.
      Contains 1 RanBP2-type zinc finger.
      Contains 2 RRM (RNA recognition motif) domains.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • FLJ39876 antibody
      • G15 antibody
      • H37 antibody
      • LUCA 15 antibody
      • LUCA15 antibody
      • Protein G15 antibody
      • Putative tumor suppressor LUCA15 antibody
      • RBM 5 antibody
      • Rbm5 antibody
      • RBM5_HUMAN antibody
      • Renal carcinoma antigen NY REN 9 antibody
      • Renal carcinoma antigen NY-REN-9 antibody
      • RMB 5 antibody
      • RMB5 antibody
      • RNA binding motif protein 5 antibody
      • RNA binding protein 5 antibody
      • RNA-binding motif protein 5 antibody
      • RNA-binding protein 5 antibody
      • Tumor suppressor LUCA15 antibody
      see all

    Anti-RBM5 antibody 画像

    • RBM5 antibody (ab56598) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human lung.
    • Western blot against tagged recombinant protein immunogen using ab56598 RBM5 antibody at 1ug/ml. Predicted band size of immunogen is 35 kDa

    Anti-RBM5 antibody (ab56598) 使用論文

    ab56598 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab56598.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"