製品の概要

  • 製品名Anti-RBM38 antibody
    RBM38 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to RBM38
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within internal amino acids 190-239 (YPYAASPATA ASFVGYSYPA AVPQALSAAA PAGTTFVQYQ APQLQPDRMQ) of human RBM38 (NP_059965).

  • ポジティブ・コントロール
    • HT1080 cell lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab94420 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 25 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation.
  • 配列類似性Belongs to the RBM38 family.
    Contains 1 RRM (RNA recognition motif) domain.
  • 細胞内局在Cytoplasm, cytosol. Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CLL associated antigen KW 5 antibody
    • CLL-associated antigen KW-5 antibody
    • HSRNASEB antibody
    • RBM38 antibody
    • RBM38_HUMAN antibody
    • RNA binding motif protein 38 antibody
    • RNA binding protein 38 antibody
    • RNA binding region (RNP1, RRM) containing 1 antibody
    • RNA binding region containing protein 1 antibody
    • RNA-binding motif protein 38 antibody
    • RNA-binding protein 38 antibody
    • RNA-binding region-containing protein 1 antibody
    • RNPC1 antibody
    • SEB4 antibody
    • SEB4B antibody
    • SEB4D antibody
    • ssDNA binding protein SEB4 antibody
    • ssDNA-binding protein SEB4 antibody
    see all

Anti-RBM38 antibody 画像

  • Anti-RBM38 antibody (ab94420) at 1 µg/ml (in 5% skim milk / PBS buffer ) + HT1080 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 25 kDa

Anti-RBM38 antibody (ab94420) 使用論文

This product has been referenced in:
  • Ding C  et al. Long non-coding RNA HOTAIR promotes cell migration and invasion via down-regulation of RNA binding motif protein 38 in hepatocellular carcinoma cells. Int J Mol Sci 15:4060-76 (2014). WB ; Human . Read more (PubMed: 24663081) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"