製品の概要

  • 製品名Anti-RBM25 antibody
    RBM25 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to RBM25
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse
    交差が予測される動物種: Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Human, Saccharomyces cerevisiae, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within internal amino acids 288-338 (

    DTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERERERERER

    ) of Mouse RBM25 Isoforms 1 and 2 (B2RY56; NM_027349).

  • ポジティブ・コントロール
    • Mouse liver lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab125311 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 99 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site (5'-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7L3 promotes U1 snRNP binding to a weak 5' ss in a 5'-CGGGCA-3'-dependent manner. Binds to the exonic splicing enhancer 5'-CGGGCA-3' RNA sequence located within exon 2 of the BCL2L1 pre-mRNA.
  • 配列類似性Contains 1 PWI domain.
    Contains 1 RRM (RNA recognition motif) domain.
  • 翻訳後修飾Sumoylated.
  • 細胞内局在Nucleus speckle. Cytoplasm. Colocalizes predominantly, with SFRS2 and LUC7L3 splicing factors, in nuclear speckles. Cytoplasmic localization is faint.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Arg/Glu/Asp rich protein, 120 kDa antibody
    • Arg/Glu/Asp-rich protein of 120 kDa antibody
    • fSAP94 antibody
    • functional spliceosome-associated protein 94 antibody
    • NET52 antibody
    • Protein S164 antibody
    • Rbm25 antibody
    • RBM25_HUMAN antibody
    • RED120 antibody
    • RNA binding motif protein 25 antibody
    • RNA binding region (RNP1, RRM) containing 7 antibody
    • RNA-binding motif protein 25 antibody
    • RNA-binding protein 25 antibody
    • RNA-binding region-containing protein 7 antibody
    • RNPC7 antibody
    • S164 antibody
    • Snu71 antibody
    • U1 small nuclear ribonucleoprotein 1SNRP homolog antibody
    see all

Anti-RBM25 antibody 画像

  • Anti-RBM25 antibody (ab125311) at 1 µg/ml + Mouse liver lysate at 10 µg

    Predicted band size : 99 kDa

Anti-RBM25 antibody (ab125311) 使用論文

ab125311 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab125311.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"