製品の概要

  • 製品名Anti-RBM10 antibody
    RBM10 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to RBM10
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 84-113 of Human RBM10 (NP_005667.2, NP_690595.1).

  • ポジティブ・コントロール
    • 293 cell line lysate

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab124060 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 104 kDa.

ターゲット情報

  • 機能May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A).
  • 関連疾患Defects in RBM10 are the cause of TARP syndrome (TARPS) [MIM:311900]. It is a disorder characterized by the Robin sequence (micrognathia, glossoptosis and cleft palate), talipes equinovarus and cardiac defects.
  • 配列類似性Contains 1 C2H2-type zinc finger.
    Contains 1 G-patch domain.
    Contains 1 RanBP2-type zinc finger.
    Contains 2 RRM (RNA recognition motif) domains.
  • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在Nucleus. In the extranucleolar nucleoplasm constitutes hundreds of nuclear domains, which dynamically change their structures in a reversible manner. Upon globally reducing RNA polymerase II transcription, the nuclear bodies enlarge and decrease in number. They occur closely adjacent to nuclear speckles or IGCs (interchromatin granule clusters) but coincide with TIDRs.
  • Information by UniProt
  • 参照データベース
  • 別名
    • DXS8237E antibody
    • G patch domain containing protein 9 antibody
    • G patch domain-containing protein 9 antibody
    • GPATC9 antibody
    • GPATCH9 antibody
    • HGNC9896 antibody
    • KIAA0122 antibody
    • MGC1132 antibody
    • MGC997 antibody
    • Rbm10 antibody
    • RBM10_HUMAN antibody
    • RNA binding motif protein 10 antibody
    • RNA binding protein 10 antibody
    • RNA binding protein S1-1 antibody
    • RNA-binding motif protein 10 antibody
    • RNA-binding protein 10 antibody
    • RNA-binding protein S1-1 antibody
    • S1-1 antibody
    • TARPS antibody
    • ZRANB5 antibody
    see all

Anti-RBM10 antibody 画像

  • Anti-RBM10 antibody (ab124060) at 1/100 dilution + 293 cell line lysate at 35 µg

    Predicted band size : 104 kDa

Anti-RBM10 antibody (ab124060) 使用論文

ab124060 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab124060.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"