製品の概要

  • 製品名Anti-Rb2 p130 antibody
    Rb2 p130 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Rb2 p130
  • 特異性ab105741 reacts with the Spa3120 domain of pRb2 p130 from Human tissues.
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Horse, Cow, Dog, Chimpanzee, Opossum, Orangutan
  • 免疫原

    Synthetic peptide with a Cysteine residue linker, corresponding to the Spa310 sequence of Rb2 p130.

  • ポジティブ・コントロール
    • LNCaP whole cell extracts.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab105741 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/5000. Predicted molecular weight: 128 kDa.
ELISA 1/75000 - 1/100000.

ターゲット情報

  • 関連性Two retinoblastoma related proteins, p107 and pRb2 / p130, which are structurally and functionally similar to the product of the retinoblastoma gene (pRb / p105), were cloned by taking advantage of their ability to bind transforming proteins of DNA tumor viruses through a particular region called the "pocket domain." Like pRb, both proteins play a fundamental role in growth control. These Rb family proteins were measured in a variety of lung neoplasms. The highest percentage of undetectable levels and the tightest inverse correlation with the histological grading and with PCNA expression in the most aggressive tumor types were found for pRb2 / p130, which may suggest an important role for this protein in the pathogenesis and progression of lung cancer.
  • 細胞内局在Nuclear
  • 参照データベース
  • 別名
    • 130 kDa retinoblastoma associated protein antibody
    • FLJ26459 antibody
    • p130 antibody
    • PRB 2 antibody
    • PRB2 antibody
    • Rb 2 antibody
    • Rb2 antibody
    • RBL 2 antibody
    • RBL2 antibody
    • RBR 2 antibody
    • RBR2 antibody
    • Retinoblastoma like 2 antibody
    • Retinoblastoma like protein 2 antibody
    • Retinoblastoma related gene antibody
    see all

Anti-Rb2 p130 antibody 画像

  • Anti-Rb2 p130 antibody (ab105741) at 1/500 dilution + LNCaP whole cell extracts
    Developed using the ECL technique

    Predicted band size : 128 kDa

Anti-Rb2 p130 antibody (ab105741) 使用論文

ab105741 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"