製品の概要

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • アイソタイプIgG2a
  • 軽鎖の種類kappa
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab57183 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 5 µg/ml.
IHC-P Use at an assay dependent concentration.
IF Use at an assay dependent concentration.

ターゲット情報

  • 機能Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation. Binds to the photoreceptor conserved element-I (PCE-1/Ret 1) in the photoreceptor cell-specific arrestin promoter.
  • 組織特異性Expressed in the developing eye and weakly expressed in the adult retina.
  • 関連疾患Defects in RAX are the cause of microphthalmia isolated type 3 (MCOP3) [MIM:611038]. Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues. Ocular abnormalities like opacities of the cornea and lens, scaring of the retina and choroid, cataractand other abnormalities like cataract may also be present.
  • 配列類似性Belongs to the paired homeobox family. Bicoid subfamily.
    Contains 1 homeobox DNA-binding domain.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • MCOP3 antibody
    • RAX antibody
    • retina and anterior neural fold homeobox antibody
    • Retina and anterior neural fold homeobox protein antibody
    • Retinal homeobox protein Rx antibody
    • RX antibody
    • RX_HUMAN antibody
    see all

Anti-RAX antibody 画像

  • Western blot against tagged recombinant protein immunogen using ab57183 RAX antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa
  • Immunohistochemical analysis of formalin-fixed paraffin-embedded human adrenal gland using ab57183 at concentration 3 ug/ml

  • Immunofluorescence analysis of HeLa cell using ab57183 at concentration 10 ug/ml

Anti-RAX antibody (ab57183) 使用論文

ab57183 has not yet been referenced specifically in any publications.

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There are currently no Abreviews or Questions for ab57183.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"