製品の概要

  • 製品名Anti-RAX antibody
    RAX 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to RAX
  • 特異性ab23340 reacts with RAX (retinal homeobox protein Rx).
  • アプリケーション適用あり: IHC-P, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow
  • 免疫原

    Synthetic peptide corresponding to Human RAX aa 1-50.
    Sequence:

    MHLPGCAPAMADGSFSLAGHLLRSPGGSTSRLHSIEAILGFTKDDGILGT


    Database link: Q9Y2V3

  • ポジティブ・コントロール
    • Jurkat cell lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab23340 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use at an assay dependent concentration.
WB Use a concentration of 0.2 - 5 µg/ml. Detects a band of approximately 32 kDa (predicted molecular weight: 38 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation. Binds to the photoreceptor conserved element-I (PCE-1/Ret 1) in the photoreceptor cell-specific arrestin promoter.
  • 組織特異性Expressed in the developing eye and weakly expressed in the adult retina.
  • 関連疾患Defects in RAX are the cause of microphthalmia isolated type 3 (MCOP3) [MIM:611038]. Microphthalmia is a clinically heterogeneous disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues. Ocular abnormalities like opacities of the cornea and lens, scaring of the retina and choroid, cataractand other abnormalities like cataract may also be present.
  • 配列類似性Belongs to the paired homeobox family. Bicoid subfamily.
    Contains 1 homeobox DNA-binding domain.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • MCOP3 antibody
    • RAX antibody
    • retina and anterior neural fold homeobox antibody
    • Retina and anterior neural fold homeobox protein antibody
    • Retinal homeobox protein Rx antibody
    • RX antibody
    • RX_HUMAN antibody
    see all

Anti-RAX antibody 画像

  • Anti-RAX antibody (ab23340) at 1 µg/ml + Jurkat cell lysate

    Performed under reducing conditions.

    Predicted band size : 38 kDa
    Observed band size : 32 kDa (why is the actual band size different from the predicted?)
  • ab23340 at 4.0 µg/ml staining human spermatophore by IHC-P.  Epithelial cells, with positive label, are indicated with arrows. Magnification 400X.

Anti-RAX antibody (ab23340) 使用論文

ab23340 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry and for your patience. It has taken some time to discuss this with our source for this antibody.

It is unfortunately difficult to say what the lighter brown staining is exactly in the IHC image provided for ab23340...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"