生理活性の詳細Potent α2 adrenergic antagonist (Ki values are 3.5 (α2A), 0.37 (α2B), 0.13 (α2C) and 63.6 nM (α2D)). Partial 5-HT receptor antagonist (Ki = 14-40 nM). Centrally active following systemic administration.
保存方法Store at Room Temperature. The product can be stored for up to 12 months.
溶解性Soluble in DMSO to 20 mM amd in water to 5 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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Timmermans PB et al. A study of the selectivity and potency of rauwolscine, RX 781094 and RS 21361 as antagonists of alpha-1 and alpha-2 adrenoceptors. J Pharmacol Exp Ther228:739-48 (1984).
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