製品の概要

  • 製品名Rat LMAN1 peptide

製品の詳細

  • 由来Synthetic
  • アミノ酸配列
    • 生物種Rat
    • 配列FDSFDNDGKKNNPAI
    • 領域159 to 173

関連製品

特性

Our Abpromise guarantee covers the use of ab39824 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-LMAN1 antibody (ab32583)

    Neutralising

  • 製品の状態Liquid
  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

関連情報

  • 別名
    • Endoplasmic reticulum golgi intermediate compartment protein 53
    • ER-Golgi intermediate compartment 53 kDa protein
    • ERGIC-53
    • ERGIC53
    • ERGIC53 like protein
    • F5F8D
    • FMFD1
    • Gp58
    • Intracellular mannose specific lectin
    • Intracellular mannose-specific lectin MR60
    • Lectin mannose binding 1
    • Lectin mannose-binding 1
    • Lman1
    • LMAN1 like protein
    • LMAN1_HUMAN
    • MCFD1
    • MR60
    • Protein ERGIC-53
    see all
  • 機能Mannose-specific lectin. May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both. The LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins.
  • 組織特異性Ubiquitous.
  • 関連疾患Defects in LMAN1 are THE cause of factor V and factor VIII combined deficiency type 1 (F5F8D1) [MIM:227300]; also known as multiple coagulation factor deficiency I (MCFD1). F5F8D1 is an autosomal recessive blood coagulation disorder characterized by bleeding symptoms similar to those in hemophilia or parahemophilia, that are caused by single deficiency of FV or FVIII, respectively. The most common symptoms are epistaxis, menorrhagia, and excessive bleeding during or after trauma. Plasma levels of coagulation factors V and VIII are in the range of 5 to 30% of normal.
  • 配列類似性Contains 1 L-type lectin-like domain.
  • 翻訳後修飾The N-terminal may be partly blocked.
  • 細胞内局在Endoplasmic reticulum-Golgi intermediate compartment membrane. Golgi apparatus membrane. Endoplasmic reticulum membrane.
  • Information by UniProt

Rat LMAN1 peptide (ab39824) 使用論文

ab39824 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"