Rat LMAN1 peptide (ab39824)
Key features and details
- Purity: > 70% HPLC
- Suitable for: Blocking, Neutralising
製品の詳細
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製品名
Rat LMAN1 peptide -
精製度
> 70 % HPLC. -
Animal free
No -
由来
Synthetic -
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生物種
Rat -
配列
FDSFDNDGKKNNPAI -
領域
159 to 173
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関連製品
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Corresponding Antibody
特性
Our Abpromise guarantee covers the use of ab39824 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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アプリケーション
Blocking - Blocking peptide for Anti-LMAN1 antibody (ab32583)
Neutralising
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製品の状態
Lyophilized -
Concentration information loading...
前処理および保存
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保存方法および安定性
Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycle.
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再構成Reconstitute with 0.1 ml of distilled water
関連情報
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別名
- Endoplasmic reticulum golgi intermediate compartment protein 53
- ER-Golgi intermediate compartment 53 kDa protein
- ERGIC-53
see all -
機能
Mannose-specific lectin. May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both. The LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins. -
組織特異性
Ubiquitous. -
関連疾患
Defects in LMAN1 are THE cause of factor V and factor VIII combined deficiency type 1 (F5F8D1) [MIM:227300]; also known as multiple coagulation factor deficiency I (MCFD1). F5F8D1 is an autosomal recessive blood coagulation disorder characterized by bleeding symptoms similar to those in hemophilia or parahemophilia, that are caused by single deficiency of FV or FVIII, respectively. The most common symptoms are epistaxis, menorrhagia, and excessive bleeding during or after trauma. Plasma levels of coagulation factors V and VIII are in the range of 5 to 30% of normal. -
配列類似性
Contains 1 L-type lectin-like domain. -
翻訳後修飾
The N-terminal may be partly blocked. -
細胞内局在
Endoplasmic reticulum-Golgi intermediate compartment membrane. Golgi apparatus membrane. Endoplasmic reticulum membrane. - Information by UniProt
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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Datasheet download
参考文献 (0)
ab39824 は論文での使用が確認できていません。