製品の概要

製品の詳細

  • 由来
    Synthetic

関連製品

特性

Our Abpromise guarantee covers the use of ab99036 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • アプリケーション

    Blocking - Blocking peptide for Anti-Calpain 2 antibody (ab88110)

  • 精製度
    70 - 90% by HPLC.

  • 製品の状態
    Liquid
  • 備考

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

関連情報

  • 別名
    • Calcium activated neutral proteinase
    • Calcium activated neutral proteinase 2
    • Calcium-activated neutral protease 2, catalytic subunit
    • Calcium-activated neutral proteinase 2
    • CALP80
    • Calpain 2 (m/II) large subunit
    • Calpain 2 catalytic subunit
    • Calpain 2 large catalytic subunit
    • Calpain 2 large subunit
    • Calpain 2, large [catalytic] subunit
    • Calpain large polypeptide L2
    • Calpain M type
    • Calpain M-type
    • Calpain-2 catalytic subunit
    • Calpain-2 large subunit
    • Calpain2
    • CAN2_HUMAN
    • CANP 2
    • CANP L2
    • CANP2
    • CANPL 2
    • CANPL2
    • CANPml
    • Capa2
    • CAPN 2
    • CAPN2
    • FLJ39928
    • M calpain
    • M calpin
    • M type
    • M-calpain
    • mCANP
    • Millimolar calpain
    • Millimolar-calpain
    see all
  • 機能
    Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
  • 組織特異性
    Ubiquitous.
  • 配列類似性
    Belongs to the peptidase C2 family.
    Contains 1 calpain catalytic domain.
    Contains 3 EF-hand domains.
  • 細胞内局在
    Cytoplasm. Cell membrane. Translocates to the plasma membrane upon Ca(2+) binding.
  • Information by UniProt

参考文献

ab99036 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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