Anti-CDC25 抗体 [EPR1790(2)] (ab111830)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR1790(2)] to CDC25
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
製品の概要
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製品名
Anti-CDC25 antibody [EPR1790(2)]
CDC25 一次抗体 製品一覧 -
製品の詳細
Rabbit monoclonal [EPR1790(2)] to CDC25 -
由来種
Rabbit -
特異性
This antibody detects the band of interest in tissue lysates, but it did not detect the protein in cell lysate.
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アプリケーション
適用あり: WBmore details
適用なし: Flow Cyt,ICC/IF,IHC-P or IP -
種交差性
交差種: Human
交差が予測される動物種: Rat -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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ポジティブ・コントロール
- Human hippocampus, hypothalamus, and midbrain lysates.
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特記事項
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Mouse: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information.
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading...
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精製度
Protein A purified -
ポリ/モノ
モノクローナル -
クローン名
EPR1790(2) -
アイソタイプ
IgG -
研究分野
関連製品
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Alternative Versions
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab111830の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/1000 - 1/10000. Predicted molecular weight: 145 kDa.
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特記事項 |
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WB
1/1000 - 1/10000. Predicted molecular weight: 145 kDa. |
ターゲット情報
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機能
Promotes the exchange of Ras-bound GDP by GTP. -
配列類似性
Contains 1 DH (DBL-homology) domain.
Contains 1 IQ domain.
Contains 1 N-terminal Ras-GEF domain.
Contains 2 PH domains.
Contains 1 Ras-GEF domain. -
ドメイン
The DH (DBL-homology) domain mediates interaction with RASGRF2. -
翻訳後修飾
Ubiquitinated. - Information by UniProt
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参照データベース
- Entrez Gene: 5923 Human
- Entrez Gene: 192213 Rat
- Omim: 606600 Human
- SwissProt: Q13972 Human
- SwissProt: P28818 Rat
- Unigene: 459035 Human
- Unigene: 135776 Rat
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別名
- CDC25 antibody
- CDC25L antibody
- GNRP antibody
see all
画像
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab111830 は 2 報の論文で使用されています。
- Jiang T et al. ALOX12B promotes carcinogenesis in cervical cancer by regulating the PI3K/ERK1 signaling pathway. Oncol Lett 20:1360-1368 (2020). PubMed: 32724378
- Watts JM et al. A Case of AML Characterized by a Novel t(4;15)(q31;q22) Translocation That Confers a Growth-Stimulatory Response to Retinoid-Based Therapy. Int J Mol Sci 18:N/A (2017). WB ; Human . PubMed: 28696354