製品の概要

  • 製品名Anti-RanBP3 antibody
    RanBP3 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to RanBP3
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment: KESLAESAAA YTKATARKCL LEKVEVITGE EAESNVLQMQ CKLFVFDKTS QSWLLRHPHP SHPAVGPCLC GEQPALCPCP GLPNYRPGTP AQLGGLLVRV , corresponding to amino acids 298-397 of Human RanBP3

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab56341 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction. In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 to the nuclear pore complex. Binds to CHC1/RCC1 and increases the guanine nucleotide exchange activity of CHC1/RCC1. Recruits XPO1/CRM1 to CHC1/RCC1 in a Ran-dependent manner. Negative regulator of TGF-beta signaling through interaction with the R-SMAD proteins, SMAD2 and SMAD3, and mediating their nuclear export.
    • 組織特異性Widely expressed with high levels in testis and heart.
    • 配列類似性Contains 1 RanBD1 domain.
    • 翻訳後修飾Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 細胞内局在Cytoplasm. Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • DKFZp586I1520 antibody
      • Ran binding protein 3 antibody
      • Ran-binding protein 3 antibody
      • RANB3_HUMAN antibody
      • RanBP3 antibody
      see all

    Anti-RanBP3 antibody 画像

    • Western blot against tagged recombinant protein immunogen using ab56341 RanBP3 antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa

    Anti-RanBP3 antibody (ab56341) 使用論文

    ab56341 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab56341.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"