製品の概要

  • 製品名Anti-Ran antibody [ARAN1]
    Ran 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [ARAN1] to Ran
  • アプリケーション適用あり: WB, IP, ELISA, ICCmore details
  • 種交差性
    交差種: Mouse, Hamster, Cow, Human, Xenopus laevis
  • 免疫原

    Denatured recombinant protein (Human).

  • エピトープThe antibody epitope is located at the C-terminus (amino acids 207-216), which is highly negatively charged.
  • ポジティブ・コントロール
    • Jurkat cells extract.
  • 特記事項Storage in frost-free freezers is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilutions should be discarded if not used within 12 hours.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab13049 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 25 kDa.
IP Use at an assay dependent dilution.
ELISA Use at an assay dependent dilution.
ICC Use at an assay dependent dilution.

ターゲット情報

  • 機能GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules.
    Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.
  • 組織特異性Expressed in a variety of tissues.
  • 配列類似性Belongs to the small GTPase superfamily. Ran family.
  • 翻訳後修飾The N-terminus is blocked.
  • 細胞内局在Nucleus. Cytoplasm. Melanosome. Becomes dispersed throughout the cytoplasm during mitosis. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Androgen receptor associated protein 24 antibody
    • Androgen receptor-associated protein 24 antibody
    • ARA 24 antibody
    • ARA24 antibody
    • Gsp1 antibody
    • GTP binding nuclear protein RAN antibody
    • GTP-binding nuclear protein Ran antibody
    • GTPase Ran antibody
    • Guanosine triphosphatase Ran antibody
    • LPS antibody
    • OK/SW-cl.81 antibody
    • ran antibody
    • RAN member RAS oncogene family antibody
    • RAN_HUMAN antibody
    • RanGTPase antibody
    • Ras like protein TC4 antibody
    • Ras related nuclear protein antibody
    • Ras-like protein TC4 antibody
    • Ras-related nuclear protein antibody
    • RASL2 8 antibody
    • TC 4 antibody
    • TC4 antibody
    see all

Anti-Ran antibody [ARAN1] (ab13049) 使用論文

ab13049 has not yet been referenced specifically in any publications.

Product Wall

Hello!

The information from the laboratory is as follows:

We would expect this antibody to recognise human, bovine, mouse, hamster, Xenopus lawvis Ran, which is approximately 25kDa.

Unfortunately we do not have information on...

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Thank you for your call yesterday and for your patience while I have been in touch with the lab regarding your enquiry.

Unfortunately we don't have any IF images available that were generated in-house, however I have found an article that con...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"