製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to RALB
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow, Zebrafish
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 1-182 of Human RALB (NP_002872).

  • ポジティブ・コントロール
    • HepG2 whole cell lysate; 293T, A431, H1299, HeLa S3, Molt-4 and Raji cell lysates

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab96456 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/3000. Predicted molecular weight: 23 kDa.

ターゲット情報

  • 機能
    Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells. Plays a role in the late stages of cytokinesis and is required for the abscission of the bridge joining the sister cells emerging from mitosis. Required for suppression of apoptosis.
  • 配列類似性
    Belongs to the small GTPase superfamily. Ras family.
  • 翻訳後修飾
    Prenylation is essential for membrane localization. The geranylgeranylated form and the farnesylated mutant does not undergo alternative prenylation in response to geranylgeranyltransferase I inhibitors (GGTIs) and farnesyltransferase I inhibitors (FTIs).
  • 細胞内局在
    Cell membrane. During late cytokinesis localizes at the midbody.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 5730472O18Rik antibody
    • dRalb antibody
    • GTP binding protein antibody
    • Ralb antibody
    • RALB_HUMAN antibody
    • RAS like protein B antibody
    • RAS like proto oncogene B antibody
    • Ras related GTP binding protein B antibody
    • Ras-related protein Ral-B antibody
    • v ral simian leukemia viral oncogene homolog B (ras related GTP binding protein) antibody
    • v ral simian leukemia viral oncogene homolog B (ras related) antibody
    • V ral simian leukemia viral oncogene homolog B antibody
    see all

画像

  • Anti-RALB antibody (ab96456) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size : 23 kDa

プロトコール

参考文献

ab96456 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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