製品の概要

  • 製品名Anti-RALB antibody [4D1]
    RALB 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [4D1] to RALB
  • アプリケーション適用あり: WB, IP, IHC-P, Sandwich ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant protein of Human RALB (NP_002872.1).

  • ポジティブ・コントロール
    • Recombinant Human RALB protein;, RALB transfected 293T cell lysate, Human Spleen tissue.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab117742 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 23 kDa.
IP Use at an assay dependent concentration. (40 ug of antibody per 100 ul of beads)
IHC-P Use a concentration of 5 µg/ml.
Sandwich ELISA Use at an assay dependent concentration.

ターゲット情報

  • 機能Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells. Plays a role in the late stages of cytokinesis and is required for the abscission of the bridge joining the sister cells emerging from mitosis. Required for suppression of apoptosis.
  • 配列類似性Belongs to the small GTPase superfamily. Ras family.
  • 翻訳後修飾Prenylation is essential for membrane localization. The geranylgeranylated form and the farnesylated mutant does not undergo alternative prenylation in response to geranylgeranyltransferase I inhibitors (GGTIs) and farnesyltransferase I inhibitors (FTIs).
  • 細胞内局在Cell membrane. During late cytokinesis localizes at the midbody.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 5730472O18Rik antibody
    • dRalb antibody
    • GTP binding protein antibody
    • Ralb antibody
    • RALB_HUMAN antibody
    • RAS like protein B antibody
    • Ras related GTP binding protein B antibody
    • Ras-related protein Ral-B antibody
    • v ral simian leukemia viral oncogene homolog B (ras related GTP binding protein) antibody
    • v ral simian leukemia viral oncogene homolog B (ras related) antibody
    • V ral simian leukemia viral oncogene homolog B antibody
    see all

Anti-RALB antibody [4D1] 画像

  • All lanes : Anti-RALB antibody [4D1] (ab117742)

    Lane 1 : 293T cell lysate, transfected with RALB
    Lane 2 : 293T cell lysate, non-transfected


    Predicted band size : 23 kDa
  • ab117742, at 5 µg/ml, staining RALB in Formalin-fixed, Paraffin-embedded Human Spleen tissue by Immunohistochem
  • Detection limit for recombinant tagged RALB is approximately 0.3ng/ml (ab117742) as a capture antibody.

Anti-RALB antibody [4D1] (ab117742) 使用論文

ab117742 has not yet been referenced specifically in any publications.

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