製品の概要

  • 製品名Anti-Rad6 antibody [2782C5]
    Rad6 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [2782C5] to Rad6
  • アプリケーション適用あり: IHC-M, WB, Dot blotmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment corresponding to Human Rad6 (internal sequence).

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab50889 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-M
WB
Dot blot
  • 追加情報Dot: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution. Predicted molecular weight: 17 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11', as well as 'Lys-48'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA.
    • パスウェイProtein modification; protein ubiquitination.
    • 配列類似性Belongs to the ubiquitin-conjugating enzyme family.
    • Information by UniProt
    • 参照データベース
    • 別名
      • BHR6A antibody
      • hHR6A antibody
      • HR6A antibody
      • mHR6A antibody
      • MRXS30 antibody
      • MRXSN antibody
      • RAD6 homolog A antibody
      • RAD6A antibody
      • UBC2 antibody
      • UBCD6 antibody
      • UBE2A antibody
      • Ube2a ubiquitin-conjugating enzyme E2A antibody
      • UBE2A_HUMAN antibody
      • Ubiquitin carrier protein A antibody
      • Ubiquitin carrier protein antibody
      • Ubiquitin conjugating enzyme E2 17 kDa antibody
      • Ubiquitin conjugating enzyme E2 21.5 kDa antibody
      • Ubiquitin conjugating enzyme E2A (RAD6 homolog) antibody
      • Ubiquitin conjugating enzyme E2A antibody
      • Ubiquitin protein ligase A antibody
      • Ubiquitin-conjugating enzyme E2 A antibody
      • Ubiquitin-protein ligase A antibody
      see all

    Anti-Rad6 antibody [2782C5] 画像

    Anti-Rad6 antibody [2782C5] (ab50889) 使用論文

    ab50889 has not yet been referenced specifically in any publications.

    Product Wall

    Abcam has not validated the combination of species/application used in this Abreview.
    Application Immunocytochemistry/ Immunofluorescence
    Sample Human Cell (HeLa)
    Specification HeLa
    Fixative Paraformaldehyde
    Permeabilization Yes - 0.5% Triton X100 in PBS
    Username

    Dr. Kirk McManus

    Verified customer

    投稿 Oct 14 2008

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"