製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to RAD52
  • アプリケーション
    適用あり: WB, IP, Electron Microscopy, ICC/IFmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length protein (Human).

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab18264 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent dilution. Predicted molecular weight: 46 kDa.
IP Use at an assay dependent dilution.
Electron Microscopy Use at an assay dependent dilution.
ICC/IF 1/100 - 1/200.

ターゲット情報

  • 機能
    Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase.
  • 配列類似性
    Belongs to the RAD52 family.
  • 翻訳後修飾
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 細胞内局在
    Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • DNA repair protein RAD52 antibody
    • DNA repair protein RAD52 antibody
    • DNA repair protein RAD52 homolog antibody
    • RAD 52 antibody
    • Rad52 antibody
    • RAD52 homolog (S. cerevisiae) antibody
    • RAD52 homolog (S. cerevisiae) antibody
    • RAD52 homolog antibody
    • RAD52_HUMAN antibody
    • Recombination protein RAD52 antibody
    • Recombination protein RAD52 antibody
    • Rhabdomyosarcoma antigen MU RMS 40.23 antibody
    see all

参考文献

This product has been referenced in:
  • Ahn JW  et al. SERBP1 affects homologous recombination-mediated DNA repair by regulation of CtIP translation during S phase. Nucleic Acids Res 43:6321-33 (2015). Read more (PubMed: 26068472) »
  • Tang KW  et al. Rad51 and Rad52 are involved in homologous recombination of replicating herpes simplex virus DNA. PLoS One 9:e111584 (2014). Human . Read more (PubMed: 25365323) »

See all 3 Publications for this product

レビューと Q&A

Thank you for your patience. The originator has informed me that they do not have the immunogen sequence for ab18264 but can say that the immunogen was a His tagged pure full length recombinant Rad52. I am sorry I can't be of more assistance in ...

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Abcam guarantees this product to work in the species/application used in this Abreview.
Application
Immunocytochemistry/ Immunofluorescence
Sample
Human Cell (HeLa)
Specification
HeLa
Fixative
Paraformaldehyde
Username

Dr. Kirk Mcmanus

Verified customer

投稿 Oct 03 2006

Thank you for your patience waiting for a response to your enquiry. I have now received details of a reference for this antibody (ab18264): The Embo Journal. 18 (22), p6552-6560 1999. The meiosis specific recombinase hDmcl forms ring structures a...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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