製品の概要

  • 製品名Anti-Rad51L1 antibody [EPR5728]
    Rad51L1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit monoclonal [EPR5728] to Rad51L1
  • アプリケーション適用あり: WB, ICC/IFmore details
    適用なし: Flow Cyt,IHC-P or IP
  • 種交差性
    交差種: Human
    非交差種: Mouse, Rat
  • 免疫原

    Synthetic peptide corresponding to N-terminal amino acids of Human Rad51L1.

  • ポジティブ・コントロール
    • MCF7 cell lysate; MCF7 cells.
  • 特記事項

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab124675 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000 - 1/10000. Detects a band of approximately 42 kDa (predicted molecular weight: 42 kDa).
ICC/IF 1/50 - 1/100.
  • 追加情報Is unsuitable for Flow Cyt,IHC-P or IP.
  • ターゲット情報

    • 機能Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. May promote the assembly of presynaptic RAD51 nucleoprotein filaments. The RAD51B-RAD51C dimer exhibits single-stranded DNA-dependent ATPase activity. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.
    • 組織特異性Expressed in a wide range of tissues.
    • 関連疾患Note=A chromosomal aberration involving RAD51L1 is found in pulmonary chondroid hamartoma. Translocation t(6;14)(p21;q23-24) with HMGA1.
      Note=A chromosomal aberration involving RAD51L1 is found in uterine leiomyoma. Translocation t(12;14)(q15;q23-24) with HMGA2.
    • 配列類似性Belongs to the RecA family. RAD51 subfamily.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • DNA repair protein RAD51 homolog 2 antibody
      • hREC2 antibody
      • MGC34245 antibody
      • OTTHUMP00000212251 antibody
      • OTTHUMP00000212253 antibody
      • OTTHUMP00000212254 antibody
      • OTTHUMP00000212255 antibody
      • R51H2 antibody
      • RA51B_HUMAN antibody
      • RAD51 homolog B (S. cerevisiae) antibody
      • RAD51 homolog B antibody
      • RAD51 like 1 antibody
      • RAD51 like protein 1 antibody
      • RAD51-like protein 1 antibody
      • Rad51B antibody
      • RAD51L1 antibody
      • REC2 antibody
      • RecA like protein antibody
      • Recombination repair protein antibody
      see all

    Anti-Rad51L1 antibody [EPR5728] 画像

    • Anti-Rad51L1 antibody [EPR5728] (ab124675) at 1/1000 dilution + MCF7 cell lysate at 10 µg

      Secondary
      Goat anti-Rabbit HRP at 1/2000 dilution

      Predicted band size : 42 kDa
    • ab124675, at 1/50 dilution, staining Rad51L1 in MCF7 cells by Immunofluorescence.
    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    Anti-Rad51L1 antibody [EPR5728] (ab124675) 使用論文

    This product has been referenced in:
    • Lee PS  et al. RAD51B Activity and Cell Cycle Regulation in Response to DNA Damage in Breast Cancer Cell Lines. Breast Cancer (Auckl) 8:135-44 (2014). WB ; Human . Read more (PubMed: 25368520) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab124675.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"