製品の概要

  • 製品名Anti-Rad1 antibody
    Rad1 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Rad1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to internal sequence amino acids 117-146 of Human Rad1 (NP_002844.1).

  • ポジティブ・コントロール
    • K562 cell line lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • バッファーPreservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)This antibody is purified through a protein A column, followed by peptide affinity purification.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab123607 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Predicted molecular weight: 32 kDa.

ターゲット情報

  • 機能Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage by the RAD17-replication factor C (RFC) clamp loader complex. Acts then as a sliding clamp platform on DNA for several proteins involved in long-patch base excision repair (LP-BER). The 9-1-1 complex stimulates DNA polymerase beta (POLB) activity by increasing its affinity for the 3'-OH end of the primer-template and stabilizes POLB to those sites where LP-BER proceeds; endonuclease FEN1 cleavage activity on substrates with double, nick, or gap flaps of distinct sequences and lengths; and DNA ligase I (LIG1) on long-patch base excision repair substrates. Isoform 1 possesses 3'->5' double stranded DNA exonuclease activity.
  • 組織特異性Expressed in testis, uterus, bladder, spleen, ovaries, lung, brain and muscle (at protein level).
  • 配列類似性Belongs to the rad1 family.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Cell cycle checkpoint protein Hrad1 antibody
    • Cell cycle checkpoint protein Rad 1 A / B antibody
    • Cell cycle checkpoint protein RAD1 antibody
    • Checkpoint control protein HRAD1 antibody
    • Checkpoint control protein RAD1 antibody
    • DNA repair exonuclease antibody
    • DNA repair exonuclease rad1 antibody
    • DNA repair exonuclease rad1 homolog antibody
    • DNA repair exonuclease REC1 antibody
    • DNA repair protein RAD1 antibody
    • EC 3.1.11.2 antibody
    • Exonuclease homolog RAD1 antibody
    • GTP-binding protein RAD antibody
    • hRAD 1 antibody
    • hRAD1 antibody
    • MGC77779 antibody
    • RAD 1 antibody
    • RAD antibody
    • RAD1 antibody
    • RAD1 homolog (S. pombe) antibody
    • RAD1 homolog antibody
    • Rad1 like DNA damage checkpoint antibody
    • Rad1 like DNA damage checkpoint protein antibody
    • RAD1, S. pombe, homolog of antibody
    • Rad1-like DNA damage checkpoint protein antibody
    • RAD1_HUMAN antibody
    • Ras associated with diabetes antibody
    • REC 1 antibody
    • REC1 antibody
    • RRAD antibody
    see all

Anti-Rad1 antibody 画像

  • Anti-Rad1 antibody (ab123607) at 1/100 dilution + K562 cell line lysate at 35 µg

    Predicted band size : 32 kDa

Anti-Rad1 antibody (ab123607) 使用論文

ab123607 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab123607.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"