製品の概要

  • 製品名Anti-RAC2 antibody (HRP)
    RAC2 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to RAC2 (HRP)
  • 標識HRP
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat
  • 免疫原

    Synthetic peptide:

    PQPTRQQKRACSLL

    , corresponding to C terminal amino acids 179-192 of Human RAC2 according to NP_002863.1.

  • ポジティブ・コントロール
    • MOLT4 lysates.
  • 特記事項

    Conjugated via amine groups to horseradish peroxidise.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C.
  • バッファーPreservative: 0.1% Proclin
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab124168 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Predicted molecular weight: 21 kDa.

ターゲット情報

  • 機能Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase.
  • 組織特異性Hematopoietic specific.
  • 関連疾患Defects in RAC2 are the cause of neutrophil immunodeficiency syndrome (NEUID) [MIM:608203].
  • 配列類似性Belongs to the small GTPase superfamily. Rho family.
  • 細胞内局在Cytoplasm. Membrane-associated when activated.
  • Information by UniProt
  • 参照データベース
  • 製品の状態Rac2 has high sequence homology with other Rac proteins. Therefore some antibodies may show cross-reactivity.
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Anti-RAC2 antibody (HRP) 画像

  • Anti-RAC2 antibody (HRP) (ab124168) at 1/1000 dilution + MOLT4 cell lysates at 35 µg
    Developed using the ECL technique

    Predicted band size : 21 kDa

Anti-RAC2 antibody (HRP) (ab124168) 使用論文

ab124168 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"