製品の概要

  • 製品名
    rac BHFF
  • 製品の詳細
    Potent, selective GABAB positive allosteric modulator
  • 生理活性の詳細
    Potent, selective GABAB positive allosteric modulator. Enhances GABAB agonist-stimulated responses in the FLIPR assay and [35S]GTPγS binding. Enhances inhibitory effect of baclofen on population spike (PS) in hippocampal slices. Orally active in vivo, displaying anxiolytic-like properties.
  • 精製度
    > 95%

製品の特性

参考文献

This product has been referenced in:
  • Maccioni P  et al. The positive allosteric modulator of the GABA(B) receptor, rac-BHFF, suppresses alcohol self-administration. Drug Alcohol Depend 109:96-103 (2010). Read more (PubMed: 20089372) »
  • Malherbe P  et al. Characterization of (R,S)-5,7-di-tert-butyl-3-hydroxy-3-trifluoromethyl-3H-benzofuran-2-one as a positive allosteric modulator of GABAB receptors. Br J Pharmacol 154:797-811 (2008). Read more (PubMed: 18536733) »

See 0 Publications for this product

レビューと Q&A

There are currently no Customer reviews or Questions for ab120318.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

登録