Anti-RAP1/RABGEF1 抗体 (ab113480)
Key features and details
- Rabbit polyclonal to RAP1/RABGEF1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
製品の概要
-
製品名
Anti-RAP1/RABGEF1 antibody -
製品の詳細
Rabbit polyclonal to RAP1/RABGEF1 -
由来種
Rabbit -
特異性
At least four isoforms of RAP1 are known to exist; ab113480 will recognize all four. ab113480 is predicted to not cross-react with other LRRFIP family members.
-
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Human -
免疫原
Synthetic peptide corresponding to Human RAP1/RABGEF1 aa 1-100 (internal sequence).
-
ポジティブ・コントロール
- Rat brain tissue lysate
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. -
バッファー
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: 99.98% PBS -
Concentration information loading...
-
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab113480の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB |
Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 79 kDa.
|
特記事項 |
---|
WB
Use a concentration of 0.5 - 1 µg/ml. Predicted molecular weight: 79 kDa. |
ターゲット情報
-
機能
Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase. -
配列類似性
Contains 1 A20-type zinc finger.
Contains 1 VPS9 domain. -
翻訳後修飾
Monoubiquitinated. -
細胞内局在
Cytoplasm. Early endosome. Recycling endosome. - Information by UniProt
-
参照データベース
- Entrez Gene: 27342 Human
- Omim: 609700 Human
- SwissProt: Q9UJ41 Human
- Unigene: 530053 Human
-
別名
- RAB guanine nucleotide exchange factor (GEF) 1 antibody
- Rab5 GDP/GTP exchange factor antibody
- Rab5ef antibody
see all
画像
プロトコール
データシートおよび資料
-
Datasheet download
参考文献 (3)
ab113480 は 3 報の論文で使用されています。
- Wang Y et al. Roles of Rufy3 in experimental subarachnoid hemorrhage-induced early brain injury via accelerating neuronal axon repair and synaptic plasticity. Mol Brain 15:35 (2022). PubMed: 35461284
- Kan L et al. TMT-based quantitative proteomic analysis of antitumor mechanism of Sporisorium reilianum polysaccharide WM-NP-60 against HCT116 cells. Int J Biol Macromol 165:1755-1764 (2020). PubMed: 33068624
- Kang L et al. RABEX-5 overexpression in gastric cancer is correlated with elevated MMP-9 level. Am J Transl Res 8:2365-74 (2016). PubMed: 27347344