製品の概要

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab21196 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA 1/64000.
WB Use a concentration of 0.3 - 1.5 µg/ml. Detects a band of approximately 110 kDa (predicted molecular weight: 89 kDa).

ターゲット情報

  • 機能
    Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3).
  • 配列類似性
    Contains 1 C2H2-type zinc finger.
    Contains 1 FYVE-type zinc finger.
    Contains 1 UIM (ubiquitin-interacting motif) repeat.
  • 細胞内局在
    Cell membrane. Early endosome membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 110 kDa protein antibody
    • FYVE finger containing Rab5 effector protein Rabenosyn 5 antibody
    • FYVE finger-containing Rab5 effector protein rabenosyn-5 antibody
    • Rabenosyn-5 antibody
    • RBNS5_HUMAN antibody
    • Zfyve20 antibody
    • zinc finger FYVE domain containing 20 antibody
    • Zinc finger FYVE domain-containing protein 20 antibody
    see all

画像



  • Predicted band size : 89 kDa


    ab21196 (0.3ug/ml) western blot detection of Rabenosin 5 from A431 cell lysate.

プロトコール

参考文献

ab21196 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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