製品の概要

  • 製品名Anti-RAB7B antibody
    RAB7B 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to RAB7B
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length human RAB7B (aa 1-199; AAH17092.1).

  • ポジティブ・コントロール
    • RAB7B transfected 293T cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab77064 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 5 µg/ml. Detects a band of approximately 22 kDa (predicted molecular weight: 22 kDa).

ターゲット情報

  • 機能Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway.
  • 組織特異性Expressed in heart, placenta, lung, skeletal muscle and peripheral blood leukocyte.
  • 配列類似性Belongs to the small GTPase superfamily. Rab family.
  • 細胞内局在Late endosome. Lysosome. Golgi apparatus > trans-Golgi network. Golgi apparatus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • MGC16212 antibody
    • MGC9726 antibody
    • RAB7 antibody
    • rab7B antibody
    • RAB7B, member RAS oncogene family antibody
    • RAB7B_HUMAN antibody
    • Ras related protein Rab 7b antibody
    • Ras-related protein Rab-7B antibody
    see all

Anti-RAB7B antibody 画像

  • All lanes : Anti-RAB7B antibody (ab77064) at 5 µg/ml

    Lane 1 : RAB7B transfected 293T cell lysate
    Lane 2 : Non-transfected transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 22 kDa
    Observed band size : 22 kDa

Anti-RAB7B antibody (ab77064) 使用論文

ab77064 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab77064.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"