製品の概要

  • 製品名Anti-RAB7B antibody
    RAB7B 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to RAB7B
  • アプリケーション適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment: DIWRGDVLAK IVPMEQSYPM VLLGNKIDLA DRKVPQEVAQ GWCREKDIPY FEVSAKNDIN VVQAFEMLAS RALSRYQSIL ENHLTESIKL SPDQSRSRCC , corresponding to amino acids 100-200 of Human RAB7B.

  • ポジティブ・コントロール
    • A431, HL60 cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab58029 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
IHC-P
  • 追加情報WB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway.
    • 組織特異性Expressed in heart, placenta, lung, skeletal muscle and peripheral blood leukocyte.
    • 配列類似性Belongs to the small GTPase superfamily. Rab family.
    • 細胞内局在Late endosome. Lysosome. Golgi apparatus > trans-Golgi network. Golgi apparatus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • MGC16212 antibody
      • MGC9726 antibody
      • RAB7 antibody
      • rab7B antibody
      • RAB7B, member RAS oncogene family antibody
      • RAB7B_HUMAN antibody
      • Ras related protein Rab 7b antibody
      • Ras-related protein Rab-7B antibody
      see all

    Anti-RAB7B antibody 画像

    • RAB7 antibody (ab58029) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human small Intestine.


    • Predicted band size : 23 kDa

    Anti-RAB7B antibody (ab58029) 使用論文

    ab58029 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab58029.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"