製品の概要

  • 製品名Anti-Rab20 antibody
    Rab20 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Rab20
  • アプリケーション適用あり: ICC/IF, WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment, corresponding to a region within amino acids 49- 200 of Human Rab20 (AAH26025).

  • ポジティブ・コントロール
    • WB: HeLa, HepG2 and HCT116 cell lysate IF: HeLa cells

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab105043 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ICC/IF 1/100 - 1/500.
WB 1/500 - 1/3000. Predicted molecular weight: 26 kDa.

ターゲット情報

  • 機能Plays a role in apical endocytosis/recycling. Plays a role in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes.
  • 組織特異性Low or absent expression in normal pancreas and stronger expression in 15 of 18 exocrine pancreatic adenocarcinomas (at protein level).
  • 配列類似性Belongs to the small GTPase superfamily. Rab family.
  • 細胞内局在Golgi apparatus. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane. Highly enriched on apical endocytic structures in polarized epithelial cells of kidney proximal tubules (By similarity). Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211).
  • Information by UniProt
  • 参照データベース
  • 別名
    • FLJ20429 antibody
    • RAB20 antibody
    • RAB20 member RAS oncogene family antibody
    • RAB20_HUMAN antibody
    • Ras related protein Rab20 antibody
    • Ras-related protein Rab-20 antibody
    see all

Anti-Rab20 antibody 画像

  • Anti-Rab20 antibody (ab105043) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

    Predicted band size : 26 kDa
  • ab105043, at a 1/200 dilution, staining Rab20 in methanol-fixed HeLa cells. Right image is costained with Hoechst 33342.

Anti-Rab20 antibody (ab105043) 使用論文

ab105043 has not yet been referenced specifically in any publications.

Product Wall

The immunogen that was used to generate ab105043 shows 81% identity with rat Rab20, so there is a possibility that it will cross-react.

I hope this is helpful. Please let me know if you have any further questions.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"