製品の概要

  • 製品名Anti-Rab11A antibody
    Rab11A 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Rab11A
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Sheep, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish, African Green Monkey
  • 免疫原

    Synthetic peptide, corresponding to a region within C terminal amino acids 160-209 (NVEAAFQTIL TEIYRIVSQK QMSDRRENDM SPSNNVVPIH VPPTTENKPK) of Human RAB11A (NP_004654).

  • ポジティブ・コントロール
    • Human placenta lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab125456 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 24 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能Regulates endocytic recycling. May exert its functions by interacting with multiple effector proteins in different complexes. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polarization. Together with RAB3IP, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis (By similarity). Together with MYO5B participates in CFTR trafficking to the plasma membrane and TF (Transferrin) recycling in nonpolarized cells. Required in a complex with MYO5B and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Participates in the sorting and basolateral transport of CDH1 from the Golgi apparatus to the plasma membrane. Regulates the recycling of FCGRT (receptor of Fc region of monomeric Ig G) to basolateral membranes.
  • 配列類似性Belongs to the small GTPase superfamily. Rab family.
  • 細胞内局在Cell membrane. Recycling endosome membrane. Cleavage furrow. Translocates with RAB11FIP2 from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane. Localizes to the cleavage furrow. Colocalizes with PARD3, PRKCI, EXOC5, OCLN, PODXL and RAB8A in apical membrane initiation sites (AMIS) during the generation of apical surface and luminogenesis.
  • Information by UniProt
  • 参照データベース
  • 別名
    • MGC1490 antibody
    • Rab 11 antibody
    • Rab 11A antibody
    • RAB 11A, member oncogene family antibody
    • Rab-11 antibody
    • RAB11 A antibody
    • RAB11 antibody
    • Rab11a antibody
    • RAB11A member RAS oncogene family antibody
    • Ras related protein Rab 11A antibody
    • Ras related protein Rab11A antibody
    • Ras-related protein Rab-11A antibody
    • RB11A_HUMAN antibody
    • YL 8 antibody
    • YL8 antibody
    see all

Anti-Rab11A antibody 画像

  • Anti-Rab11A antibody (ab125456) at 1 µg/ml + Human placenta lysate at 10 µg

    Secondary
    Goat anti-Rabbit IgG-HRP

    Predicted band size : 24 kDa

Anti-Rab11A antibody (ab125456) 使用論文

ab125456 has not yet been referenced specifically in any publications.

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