製品の概要

  • 製品名Anti-RAB11-FIP2 antibody
    RAB11-FIP2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to RAB11-FIP2
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 71-120 (LLIQGSPEKY ILFLIVMHRS LVGLDKFLGQ VAINLNDIFE DKQRRKTEWF) of Human RAB11-FIP2 (NP_055719).

  • ポジティブ・コントロール
    • COLO205 cell lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab104723 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 58 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity.
  • 配列類似性Contains 1 C2 domain.
    Contains 1 FIP-RBD domain.
  • 翻訳後修飾Phosphorylation at Ser-227 by MARK2 regulates epithelial cell polarity.
  • 細胞内局在Cell membrane. Recycling endosome membrane. Translocates with RAB11A from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • KIAA0941 antibody
    • NRip11 antibody
    • RAB11 family interacting protein 2 (class I) antibody
    • Rab11 family-interacting protein 2 antibody
    • RAB11 FIP2 long isoform antibody
    • Rab11-FIP2 antibody
    • RAB11FIP2 antibody
    • RFIP2 antibody
    • RFIP2_HUMAN antibody
    see all

Anti-RAB11-FIP2 antibody 画像

  • Anti-RAB11-FIP2 antibody (ab104723) at 1 µg/ml + COLO205 cell lysate at 10 µg

    Predicted band size : 58 kDa

Anti-RAB11-FIP2 antibody (ab104723) 使用論文

ab104723 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"