製品の概要

  • 製品名
    (R)-CPPene (SDZ EAA 494)
  • 製品の詳細
    Potent competitive NMDA antagonist
  • 別名
    • D-CPP ene
    • Midafotel
    • SDZ EAA 494
  • 生理活性の詳細
    Potent competitive NMDA antagonist. Centrally active following systemic administration.

    Also available in simple stock solutions (ab146715) - add 1 ml of water to get an exact, ready-to-use concentration.
  • 精製度
    > 98%

製品の特性

参考文献

This product has been referenced in:
  • Park CK  et al. Efficacy of D-CPPene, a competitive N-methyl-D-aspartate antagonist in focal cerebral ischemia in the rat. Neurosci Lett 147:41-4 (1992). Read more (PubMed: 1480321) »
  • Lowe DA  et al. D-CPP-ene (SDZ EAA 494), a potent and competitive N-methyl-D-aspartate (NMDA) antagonist: effect on spontaneous activity and NMDA-induced depolarizations in the rat neocortical slice preparation, compared with other CPP derivatives and MK-801. Neurosci Lett 113:315-21 (1990). Read more (PubMed: 2166255) »
  • Patel S  et al. Anticonvulsant activity of the NMDA antagonists, D(-)4-(3-phosphonopropyl) piperazine-2-carboxylic acid (D-CPP) and D(-)(E)-4-(3-phosphonoprop-2-enyl) piperazine-2-carboxylic acid (D-CPPene) in a rodent and a primate model of reflex epilepsy. Epilepsy Res 7:3-10 (0). Read more (PubMed: 2292244) »

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