製品の概要

  • 製品名
    QX-314 bromide (N-Ethyllidocaine bromide)
  • 製品の詳細
    Na+ channel blocker
  • 別名
    • N-Ethyllidocaine bromide
  • 生理活性の詳細
    A membrane impermeable quaternary lidocaine derivative. Blocks voltage-sensitive Na+ conductance when applied intracellularly.

    Also available in simple stock solutions (ab144492) - add 1 ml of water to get an exact, ready-to-use concentration.
  • 精製度
    > 99%

製品の特性

参考文献

This product has been referenced in:
  • Colling SB & Wheal HV Fast sodium action potentials are generated in the distal apical dendrites of rat hippocampal CA1 pyramidal cells. Neurosci Lett 172:73-96 (1994). Read more (PubMed: 8084540) »
  • Butterworth J  et al. Inhibition of brain cell excitability by lidocaine, QX314, and tetrodotoxin: a mechanism for analgesia from infused local anesthetics? Acta Anaesthesiol Scand 37:516-23 (1993). Read more (PubMed: 8356868) »
  • Strichartz GR The inhibition of sodium currents in myelinated nerve by quaternary derivatives of lidocaine. J Gen Physiol 62:37-57 (1973). Read more (PubMed: 4541340) »

See all 11 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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