製品の概要

  • 製品名
    Quipazine dimaleate
  • 製品の詳細
    5-HT receptor agonist
  • 生理活性の詳細
    5-HT receptor agonist, shows some selectivity at 5-HT3 (EC50 = 24 nM). Displays antidepressant and anorectic effect. Also promotes cellular proliferation.
  • 精製度
    > 99%

製品の特性

参考文献

This product has been referenced in:
  • Liu Y & Zhang ZY Serotonin receptor agonist quipazine promotes proliferation and apoptosis of human hepatocyte strain of L-02 strain. Hepatobiliary Pancreat Dis Int 8:278-81 (2009). Read more (PubMed: 19502168) »
  • Dubin AE  et al. The pharmacological and functional characteristics of the serotonin 5-HT(3A) receptor are specifically modified by a 5-HT(3B) receptor subunit. J Biol Chem 274:30799-810 (1999). Read more (PubMed: 10521471) »
  • Shukla R  et al. Evidence for 5-HT2 receptor mediation in quipazine anorexia. Psychopharmacology (Berl) 100:115-8 (1990). Read more (PubMed: 2296618) »
  • Lansdown MJ  et al. Antagonism of 5-hydroxytryptamine receptors by quipazine. Br J Pharmacol 68:525-32 (1980). Read more (PubMed: 7052342) »

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